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The human brain creates its' own psychedelic drugs.

Depression and other mental health problems can act like weed killer, shriveling these connections and making it harder to function cognitively. This is known as the neurotrophic theory of depression and psychedelic drugs like ketamine (which is also a dissociative anesthetic) seem to reverse this relationship.

New research illuminates how the human brain creates its own psychedelic drugs | Salon.com

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