Michael Pollan writes of his own consciousness-expanding experiments with psychedelic drugs and makes the case for why shaking up the brain's old habits could be therapeutic for people facing addiction, depression, or death. Here is a link to the docuseries version of Pollan’s book:
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While there is no doubt that ketamine does something helpful on a chemical level, this may not be the whole story. The problem with this paradigm of treatment is that it puts the patient in a passive
Depression and other mental health problems can act like weed killer, shriveling these connections and making it harder to function cognitively. This is known as the neurotrophic theory of depression